Journal: JMIR Mental Health

Article Title: Wearable and Mobile Technologies for the Evaluation and Treatment of Obsessive-Compulsive Disorder: Scoping Review

doi: 10.2196/45572

Figure Lengend Snippet: Studies with digital or mobile interventions, organized by publication year.

Article Snippet: Provenza et al [ ], 2021, United States , Adult men and women (31-40) , Summit RC+S (Medtronic); Apple Watch (Apple Inc); StriveStudy mobile app (Rune Labs); Honeycomb task app; actiCAP electroencephalogram cap (Brain Products GmbH); GoPro Hero 6 (GoPro Inc); H4n Pro 4-track Portable Recorder (Zoom Corp); and AFAR n computer-vision (Carnegie Mellon University) , Intracranial electrophysiology: passive collection through DBS device Heart rate, blood volume pulse, and acceleration: passive collection through Apple Watch OCD symptom severity: active collection through self-report via StriveStudy app Performance on cognitive and behavioral tasks: active collection through Honeycomb app Extracranial electrophysiology: passive collection through actiCAP Facial movements: passive collection through GoPro and AFAR Speech: passive collection through H4n recorder , Symptom burden: active collection through clinician-administered measures , Open-loop DBS to bilateral VC/VS or BNST o , Natural environment and outpatient , To identify the neural biomarkers of OCD through (1) the measurement of intracranial and extracranial electrophysiology, (2) self-reported OCD symptom burden, (3) objectively measured affective state, and (4) the evaluation of physiology for the purpose of developing an adaptive DBS for OCD , AFAR software estimated positive affect and head velocity, and these data were synchronized with blood volume pulse, electrocardiogram, electroencephalogram, LFP from DBS, and the acceleration of INS p Increase in positive affect and subjective positive feelings during DBS programming session in participant 5 Self-reports were synchronized to at-home, wirelessly streamed DBS LFP, routine at-home tasks, and psychophysiological tasks In total, across the 3 participants, over 1000 hours of at-home intracranial physiology was recorded 1 participant completed an at-home LFP recording for 3 continuous days; 41 OCD symptom intensity ratings were collected during this period (range 0-8); LFP frequency band power was examined in the minute before and after self-report; there was a strong negative correlation between power in the delta band and OCD symptom severity in both the left (R=−0.593) and right (R=−0.557) VC/VS; correlations to planned ERP exposures in this participant were also seen in the delta band.

Techniques: Software, Biomarker Assay